top of page
Writer's pictureRayki Goh, MSc

Scientific Facts on How Antioxidants Keep You Healthy

Are you concerned about maintaining your health and preventing chronic diseases? Antioxidants neutralize harmful free radicals in the body, significantly reducing oxidative stress. What are the most effective ways to incorporate antioxidants into your daily routine?

antioxidant

Dear food people,

 

The human body is capable of naturally synthesising certain antioxidants internally. One of the most important antioxidants produced in the cells is glutathione, which is composed of three amino acids: glutamine, glycine, and cysteine. Glutathione plays a crucial role in protecting cells from damage by neutralising free radicals and reactive oxygen species. Another significant antioxidant is superoxide dismutase (SOD). This enzyme helps break down superoxide radicals into oxygen and hydrogen peroxide, substances that are less harmful to the body.

 

Superoxide radicals (O₂⁻) are highly reactive molecules that form as a byproduct of oxygen metabolism in cells. They are a type of Reactive Oxygen Species (ROS) that can cause significant damage to cells by reacting with various cellular components like DNA, proteins, and lipids. This process is known as oxidative stress.

 

Hydrogen peroxide (H₂O₂) is a reactive oxygen species (ROS) that plays multiple roles in the human body, both beneficial and potentially harmful. However, the enzyme catalase assists in converting hydrogen peroxide into water and oxygen, thereby reducing its potential damage. In other words, oxidative damage is inevitable and is a naturally occurring byproduct of the body's process of using oxygen.

 

Coenzyme Q10, also known as ubiquinone, is another antioxidant naturally synthesised by the body. It is present in all cells and is essential for energy production and protecting cells from oxidative damage.

 

Antioxidants are vital for maintaining our health and they function like "free-radical scavengers" that neutralises harmful free radicals present in our bodies. Free radicals are highly reactive molecules with unpaired electrons. Due to their high reactivity, they can cause damage to cells, proteins, and DNA by interacting with other molecules. However, when met with antioxidant molecules, they donate an electron to stabilise these unstable molecules, thereby preventing cellular damage.

 

When the production of free radicals exceeds the body's antioxidant defences, it results in oxidative stress, a condition linked to numerous health issues such as cancer, heart disease, and vision loss. Thus, there is where dietary antioxidants are required to support the body and protect it from adverse effects. While the body can naturally synthesise these antioxidants, it still benefits from external sources found in foods such as fruits, vegetables, nuts, and grains. These dietary sources provide additional protection against oxidative stress, complementing the body’s internal antioxidant mechanisms.


Dietary antioxidants, which are abundantly found in fruits, vegetables, and other plant-based foods, complement the body's natural defences. Examples of these dietary antioxidants include vitamins A, C, and E, beta-carotene, lycopene, selenium, and various phytonutrients like flavonoids and polyphenols.

 

It's noteworthy that while diets rich in antioxidants are consistently associated with improved health outcomes, antioxidant supplements have not demonstrated the same benefits in scientific studies. The intricate interactions between different antioxidants in whole foods may be crucial to their health-promoting effects.

 

Incorporating a variety of antioxidant-rich foods into your diet is beneficial for supporting your body's defence system against oxidative stress and related health issues. However, relying on whole foods rather than supplements seems to be the most effective approach to harness these benefits.

 


HOW COOKING AFFECTS ANTIOXIDANT LEVELS IN FOOD

Understanding how cooking methods impact antioxidant levels in food can help you make better nutritional choices. Cooking methods can either increase or decrease antioxidants in food. For instance, boiling may reduce antioxidants as they leach into the water, while steaming retains more. Frying can enhance or reduce antioxidants, depending on the oil and temperature. Roasting and grilling can reduce antioxidants if not done carefully, but high-heat grilling might retain them better. Microwaving can preserve antioxidants well, especially with minimal water. Using a variety of cooking methods can help you maximise the antioxidants in your diet, supporting overall health. Here are some explanations of the different cooking methods:

 

Water-Based Cooking Methods

Boiling and pressure-cooking are common methods that often lead to the greatest losses of antioxidants in vegetables. This is because water-soluble antioxidants can leach into the cooking water, reducing their levels in the food itself. For example, when you boil or pressure-cook vegetables like spinach or broccoli, a significant amount of their antioxidants may end up in the water rather than on your plate.

 

Microwaving and Griddle-Cooking

Microwaving and griddle-cooking are methods that tend to preserve higher levels of antioxidants compared to boiling. These methods involve less water, which helps retain more antioxidants in the food. For instance, microwaving vegetables like bell peppers can maintain more of their beneficial compounds.

 

Dry-Heat Cooking Methods

Dry-heat methods, such as stir-frying and roasting, are effective at preserving antioxidants in foods. This is particularly true for vegetables like red peppers. Unlike boiling or steaming, these methods do not involve water, which means fewer antioxidants are lost during the cooking process.


Increased Antioxidant Levels in Some Vegetables

Interestingly, some vegetables show an increase in antioxidant levels after cooking, regardless of the method used. Green beans, celery, and carrots are examples of vegetables that can have higher antioxidant levels post-cooking. This increase is believed to be due to the breakdown of cell walls, which makes the antioxidants more available.

 

Impact of Cooking Duration

The duration of cooking also plays a critical role in antioxidant retention. Shorter cooking times tend to preserve more antioxidants. For example, blanching mung bean sprouts for just 20 seconds preserves more antioxidants than boiling them for a full minute.

 

Liberation of Antioxidant Compounds

In some cases, cooking can actually enhance the antioxidant activity of foods. This happens because the heat can liberate antioxidant compounds from the insoluble portions of foods. Additionally, heat treatment can lead to the formation of new antioxidant compounds, such as those produced during the Maillard reaction, which occurs when food is browned.

 

FUN FACT!

The Maillard reaction is a complex chemical process that occurs when proteins and sugars in food are exposed to heat, leading to the formation of new flavour compounds and browning. This reaction is responsible for the delicious flavours and aromas of roasted coffee, baked bread, and grilled meats. While the Maillard reaction can produce potentially harmful compounds like acrylamide, it can also lead to the formation of beneficial antioxidant compounds.


Formation of Antioxidant Compounds via Maillard Reaction – Explained

During the Maillard reaction, the interaction between amino acids and reducing sugars creates a variety of new molecules. Some of these molecules have antioxidant properties, meaning they can help neutralise harmful free radicals in the body. For example, melanoidins, which are brown pigments formed during the Maillard reaction, have been shown to possess antioxidant activity. These compounds can scavenge free radicals and chelate metal ions, thereby reducing oxidative stress.

 

Balancing the Pros and Cons Cooking with Heat

While it's true that the Maillard reaction can produce acrylamide, a compound linked to health risks, it's important to balance this concern with the benefits of the antioxidants that are also formed. Acrylamide typically forms in starchy foods like potatoes and bread when they are cooked at high temperatures. However, the levels of acrylamide can be minimised by using certain cooking techniques, such as avoiding excessive browning and cooking at lower temperatures for longer periods.

 

Roasted Coffee

Roasted coffee is a great example to illustrate the dual nature of the Maillard reaction. Raw coffee beans are composed of various compounds, including carbohydrates (mainly sugars like sucrose), proteins (which contain amino acids), lipids, water, and other minor components. Particularly, sugars and amino acids are crucial for the Maillard reaction. When coffee beans are roasted, they are exposed to high temperatures, typically ranging from 180°C to 240°C. During this roasting process, the heat causes the amino acids and reducing sugars within the beans to interact, initiating the Maillard reaction. The roasting process enhances the flavour and aroma of coffee beans through the Maillard reaction, resulting in the formation of melanoidins (pronounced as "mel-uh-noy-dinz"). These melanoidins not only contribute to the rich colour and taste of coffee but also have antioxidant properties. Studies have shown that coffee consumption is associated with various health benefits, partly due to the antioxidants formed during roasting.

 

FUN FACT!

During the Maillard reaction in coffee beans, numerous flavour compounds are created. For instance, the reaction can produce pyrazines, which contribute to nutty and earthy flavours, and furans, which add sweet, caramel-like notes. The balance and concentration of these compounds depend on the specific roasting conditions, such as temperature and time.


Roasted Vegetables

Roasting vegetables like carrots, sweet potatoes, and bell peppers can also illustrate the formation of beneficial compounds through the Maillard reaction. The roasting process intensifies the flavours and colours of these vegetables while creating new antioxidant compounds. Similar to those of roasted coffee beans, the antioxidant molecules are Melanoidins, Pyrazines, Furans, Pyrroles, and Strecker Aldehydes. These molecules are specifically formed or enhanced through the Maillard reaction, contributing to the antioxidant capacity of roasted vegetables.



Variation Among Different Vegetables

The effect of cooking on antioxidant levels varies widely among different vegetables. Artichokes, for example, maintain high antioxidant levels across all cooking methods. In contrast, vegetables like cauliflower, peas, and zucchini can lose a significant amount of their antioxidants when boiled or microwaved.

 


WHAT IS THE MAXIMUM ABSORPTION OF ANTIOXIDANTS ACROSS DIFFERENT AGE GROUPS?

Understanding how antioxidant absorption changes across different age groups is really important for improving health and wellness through diet. Research in this field gives us valuable information about what affects antioxidant absorption and capacity at different stages of life. This knowledge helps us make better dietary choices and can guide recommendations for different age groups to enhance overall well-being.

 

Antioxidant absorption can vary significantly between individuals and age groups due to factors like metabolism, gut health, and overall diet. Generally, young adults tend to have higher antioxidant absorption capacities compared to older adults. For example, a study found that serum Total Antioxidant Capacity (TAC) in young people aged 16-35 years was 79% lower than in middle-aged and elderly individuals.

 

Total Antioxidant Capacity is a measure used to quantify the antioxidant levels present in a biological sample, such as blood serum, food, or other substances. Antioxidants are compounds that protect cells from damage caused by free radicals, which are unstable molecules that can cause oxidative stress and contribute to various diseases and aging processes.

 

Children's ability to absorb antioxidants also shows significant variation based on their health status. Research indicates that healthy children aged 8-10 years have higher antioxidant capacity values (245 mmol Trolox/day) compared to their peers with health conditions. Obese children showed a lower absorption rate of 80.3 mmol Trolox/day, while celiac children and those with milk allergies had values of 81.3 mmol Trolox/day and 97.7 mmol Trolox/day, respectively. Additionally, children aged 2-6 years exhibited significantly higher levels of oxidative stress markers (d-ROMs) and lower antioxidant capacity compared to older children and adults. However, the antioxidant capacity tends to increase with age, as indicated by the BAP/d-ROMs ratio, which rises significantly in older children and adolescents.

 

In adults, the pattern of antioxidant capacity continues to evolve. Middle-aged and older adults generally exhibit higher antioxidant capacities compared to younger individuals. However, adults over 75 years old experience a significant reduction in total antioxidant capacity compared to younger adults (20-40 years old), along with a decrease in the mass of antioxidant substances and average activity levels in serum. Interestingly, men aged 20-25 and women aged 32-39 have been found to have higher levels of specific antioxidant enzymes, such as superoxide dismutase and catalase, compared to other age groups.

 

There is no established maximum absorption limit for antioxidants, but studies suggest that consuming these nutrients through a varied diet rich in fruits, vegetables, and whole grains is more beneficial than taking high-dose supplements. The body's ability to absorb and utilise antioxidants may plateau at certain levels, indicating that extremely high intakes do not necessarily provide additional health benefits.

 

Optimal antioxidant intake should ideally come from a balanced diet rather than supplements. The complex interactions between different antioxidants in whole foods appear to be key to their health-promoting effects. Understanding these nuances helps in making informed dietary choices for better health across different age groups. Factors like diet, lifestyle, and overall health status can significantly influence antioxidant capacity within age groups, emphasising the importance of a holistic approach to nutrition and health.




HOW CAN PAIRING ANTIOXIDANTS WITH HEALTHY FATS BOOST THEIR EFFECTIVENESS?

 

Firstly, it's essential to know that many crucial antioxidants, such as vitamins A, D, E, and K, are fat-soluble. This means they need the presence of fats to be optimally absorbed in the digestive tract. When these antioxidants are consumed with fats, their absorption is significantly improved. For instance, adding olive oil to tomatoes increases the body's uptake of lycopene, a powerful antioxidant found in tomatoes.

 

Additionally, antioxidants can offer protective effects. For example, antioxidants in red wine can help protect against the oxidation of fats in red meat during digestion, reducing the formation of harmful compounds like malondialdehyde (MDA) in the stomach.

 

The combination of antioxidants and healthy fats can also create synergistic effects. The antioxidants in vegetables can help protect the unsaturated fats in oils from oxidation, while the fats enhance the absorption of the antioxidants. This interplay enhances the overall effectiveness of both nutrients.

 

Moreover, fats are crucial for the structure and function of cell membranes. When antioxidants are consumed with fats, they may be more easily incorporated into cell membranes, potentially increasing their effectiveness at the cellular level. The presence of fats can also slow down digestion and absorption, leading to a more sustained release of antioxidants in the body.

 

By pairing antioxidants with healthy fats, you can maximise their absorption, enhance their protective effects, and potentially increase their overall bioavailability and effectiveness in the body. This synergy not only boosts the health benefits of your diet but also ensures that your body gets the most out of these vital nutrients.

 

Here are some tips to maximise antioxidant absorption from whole foods:

 

Pairing Antioxidant-Rich Foods with Healthy Fats

To improve the absorption of fat-soluble antioxidants like vitamins A, D, E, and K, it is beneficial to consume them with healthy fats. For example, adding olive oil to vegetables or eating nuts with fruits can significantly boost antioxidant uptake.

 

Combining Vitamin C with Iron-Rich Plant Foods

Vitamin C plays a vital role in enhancing the absorption of non-heme iron found in plant sources. A practical way to do this is by adding lemon juice to spinach salads or pairing berries with lentil dishes, making the iron more bioavailable.

 

Lightly Cooking Some Vegetables

Cooking methods such as steaming can increase the bioavailability of certain antioxidants in vegetables like tomatoes, carrots, and spinach. Light cooking helps release these beneficial compounds without significant nutrient loss.

 

Eating a Variety of Colourful Fruits and Vegetables

Each colour of fruits and vegetables represents different types of antioxidants. Incorporating a rainbow of options into your diet ensures you receive a wide range of these protective compounds, enhancing overall health.

 

Consuming Antioxidant-Rich Foods Regularly

Some antioxidants, such as vitamin C, are not stored long-term in the body. Therefore, regular consumption is necessary to maintain adequate levels. Integrating antioxidant-rich foods into your daily diet ensures a consistent supply.

 

Choosing Whole Foods Over Supplements

Whole foods offer complex interactions between different antioxidants, which appear to be key to their health benefits. Instead of relying on supplements, focus on incorporating a variety of whole foods into your meals.

 

Pairing Turmeric with Black Pepper

Black pepper contains piperine, which enhances the absorption of curcumin, the active antioxidant in turmeric. Adding a pinch of black pepper when using turmeric in your dishes can maximise its health benefits.

 

Keeping the Skin on Fruits and Vegetables

The skin of many fruits and vegetables is rich in antioxidants. Whenever possible, consume produce with the skin on to take full advantage of these nutrients.

 

Considering Frozen Produce

Frozen fruits and vegetables can retain high levels of antioxidants and may even be more nutritious than older "fresh" produce. They are a convenient and reliable option to ensure a steady intake of antioxidants.

 

Using Minimal Water When Cooking

When boiling vegetables, use as little water as possible and consider saving the cooking water for soups or smoothies to retain the leached nutrients. This practice helps preserve the antioxidant content of the food.


And hey, feel free to drop us a message at me@obsideonmedia.com if you've got something to say or a question to ask. Let's keep the conversation going and make food sustainability a part of our daily habits together.

 


 

Further reading:

  1. [PDF] Influence of Cooking Methods on Antioxidant Activity of Vegetables https://www.naturaleater.com/science-articles/133-cooking-methods-vegetable-antioxidants.pdf

  2. Antioxidant Levels In Cooked Vegetables Vary With ... - ScienceDaily https://www.sciencedaily.com/releases/2009/04/090415163730.htm

  3. Antioxidants and the skin: understanding formulation and efficacy https://pubmed.ncbi.nlm.nih.gov/22913443/

  4. Antioxidants in dermatology - PMC - NCBI https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514576/

  5. Antioxidants - The Nutrition Source https://nutritionsource.hsph.harvard.edu/antioxidants/

  6. Antioxidant Levels In Cooked Vegetables Vary With ... - ScienceDaily https://www.sciencedaily.com/releases/2009/04/090415163730.htm

  7. Biochemistry of Antioxidants: Mechanisms and Pharmaceutical ... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776363/

  8. Dietary antioxidant intake in school age and lung function ... https://erj.ersjournals.com/content/55/2/1900990

  9. Evaluation of oxidative stress and antioxidant capacity in healthy ... https://journals.lww.com/jcma/fulltext/2019/08000/evaluation_of_oxidative_stress_and_antioxidant.10.aspx

  10. Food synergy: an operational concept for understanding nutrition https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731586/

  11. Food Antioxidants and Their Interaction with Human Proteins - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135064/

  12. Human Bioavailability of Vitamins - Cambridge University Press https://www.cambridge.org/core/services/aop-cambridge-core/content/view/2F36AA9D8173C1773004A35DC88D3A51/S0954422494000090a.pdf/human_bioavailability_of_vitamins.pdf

  13. Serum antioxidant status among young, middle-aged and elderly ... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738412/

  14. Systemic antioxidants and skin health - ResearchGate https://www.researchgate.net/publication/233332516_Systemic_antioxidants_and_skin_health



 

The information provided in our articles is for educational and entertainment purposes only. It is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified healthcare provider with any questions you may have regarding a medical condition. The content on our website, including articles, is not meant to endorse or promote any specific medical treatments, products, or procedures. The information provided is based on general knowledge and research at the time of writing. Medical practices and knowledge are constantly evolving, and what may have been accurate at the time of publication may not be current or applicable today.




bottom of page